4-Hydroxy Isoleucine

4-hydroxyisoleucine

4-hydroxyisoleucine (Fenugreek extract)

Latin Name: Trigonella foenum-gracum L.

Active ingredient: 4-hydroxyisoleucine

Purity: 20%

 

Fenugreek’s most well-known compound is 4-hydroxyisoleucine, which works to normalize glucose metabolism.

4-Hydroxyisoleucine (HIL) from fenugreek (Trigonella foenum-graecum) seeds is a potential insulinotropic (anti-diabetic) and anti-obesity amino acid. HIL stimulates glucose-dependent insulin secretion from pancreatic cells. HIL activates insulin receptor substrate-associated phosphoinositide 3 (PI3) kinase activity. HIL reduces plasma levels of triglycerides, free fatty acids and cholesterol.

With CAS number 55399-93-4, and the popular specifications available on the market are 20% 4-hydroxyisoleucine and 40% 4-hydroxyisoleucine. The 4-hydroxyisoleucine help stimulate the secretion of insulin from your pancreas, reduce insulin resistance, and decrease blood sugar levels in diabetes patients. It also helps to enhance the glucose tolerance and reduces the amount of cholesterol efficiently.

 

Appearance	Brown yellow fine powder with characteristic odor	Visual
Identification	Passes all criteria tests	HPLC(Aidu Criteria)
Assay(4-Hydroxy-isoleucine)	≥20.0%	HPLC(Aidu  Criteria)
Loss On Drying	≤5.0%	USP〈731〉
Ash	≤5.0%	C561
Sieve	80 Mesh	USP〈786〉
Heavy Metals	≤10 mg/kg	USP〈231〉Method II
Pb	≤1.5 mg/kg	ICP-MS
As	≤1.0 mg/kg	ICP-MS
Hg	≤0.5 mg/kg	ICP-MS
Cd	≤0.5 mg/kg	ICP-MS
Residual Solvent	≤5,000 mg/kg	GC
Pesticide Residue	Meet USP〈561〉	USP〈561〉

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