PureGBB™: “Thermogenic Sweat Catalyst”, as a form a “Super Carnitine” capable of increasing carnitine excretion up to 300%. [1,2]


Meet PureGBB™
PureGBB™ is a nutritional supplement form of Gamma-butyrobetaine ethyl ester chloride manufactured by Shanghai Aidu Biotechnology Co.,Ltd and is a common ingredient in many dietary supplements.


PureGBB™ (Gamma-butyrobetaine ethyl ester chloride) is a carnitine precursor known to significantly increase carnitine levels in humans, commonly call as “Super Carnitine”.

PureGBB™ supports greater fat burning, and anecdotally produces an intense thermogenic sensation, also call as “Thermogenic Sweat Catalyst”.

PureGBB™ also supports greater utilization and storage of carnitine, aiding the body’s natural ability to mobilize and burn fatty acids for energy.

PureGBB™ can be stacked with many standalone fat burning ingredients, thermogenics and pre-workouts.


PureGBB™ (Gamma-butyrobetaine ethyl ester chloride):
Assay: 98% min
CAS No. 51963-62-3
Appearance: White to off-white crystalline powder


PureGBB™ Benefits:

1. WEIGHT LOSS THROUGH THERMOGENESIS
PureGBB™ has shown to increase thermogenesis in the body and as a result, sweat levels increase too. Thermogenic agents help increase adrenaline, a hormone that stimulates your fat cells to release fatty acids into your bloodstream. Where they are used by your cells for energy, resulting in increased fat burned. [1]


2. INCREASES FAT OXIDATION
PureGBB™ maximises the breakdown of fatty acids within the body and uses fat as a fuel instead of carbohydrates. Increased Carnitine production makes this process occur.


To create energy, the fatty acids enter the mitochondria - the energy factories of our cells. They are then transformed into carbon dioxide, heat and water, making something called ATP in the process. Once converted into ATP, the energy can then be used by the cell to power activities such as exercise, resulting in increased fat burned. [3]


3. INCREASED ENERGY
PureGBB™ enhances L-Carnitine levels which are effective in fuelling your workouts. L-Carnitine helps increase the production of red blood cells which increases the transportation of oxygen throughout your body and muscles. It acts as a great fuel source to help reach peak performance.


4. ENHANCED BRAIN FUNCTION
Studies have shown that PureGBB™ and L-Carnitine have positive effects on brain function. PureGBB™ and L-Carnitine are both useful agents in reversing the decline in brain function associated with brain diseases, including Alzheimer’s. They help to protect the brain from cell damage. [4]


5. SUPPORTS NITRIC OXIDE PRODUCTION FOR IMPROVED BLOOD FLOW
The unique aspect of PureGBB™ is its consistent impact on nitric oxide levels. At least a few studies have showed PureGBB™ to be a potent vasodilator. By improving blood flow, will probably help get nutrients to damaged muscle and joint tissue at a more rapid rate. It may even help keep blood pressure down. [5]


References:
[1] Charles J. Rebouche, E. Peter Bosch, Catherine A. Chenard, Kay J. Schabold, Steven E. Nelson; “Utilization of Dietary Precursors for Carnitine Synthesis in Human Adults”; The Journal of Nutrition, Volume 119, Issue 12, 1 December 1989, Pages 1907–1913; https://academic.oup.com/jn/article-abstract/119/12/1907/4738183
[2] Ann Louise Olson, Charles J. Rebouche; “γ-Butyrobetaine Hydroxylase Activity is Not Rate Limiting for Carnitine Biosynthesis in the Human Infant”; The Journal of Nutrition, Volume 117, Issue 6, 1 June 1987, Pages 1024–1031; https://academic.oup.com/jn/article-abstract/117/6/1024/4768474
[3] U.S. Department of Health and Human Services. (n.d.). Office of dietary supplements - carnitine. NIH Office of Dietary Supplements. Retrieved January 19, 2023, from https://ods.od.nih.gov/factsheets/Carnitine-HealthProfessional/
[4] Spagnoli A;Lucca U;Menasce G;Bandera L;Cizza G;Forloni G;Tettamanti M;Frattura L;Tiraboschi P;Comelli M; (n.d.). Long-term acetyl-l-carnitine treatment in alzheimer's disease. Neurology. Retrieved January 19, 2023, from https://pubmed.ncbi.nlm.nih.gov/1944900/
[5] Sjakste, N., Kleschyov, A. L., Boucher, J., Baumane, L., Dzintare, M., Meirena, D., Kalvinsh, I. (2004). Endothelium- and nitric oxide-dependent vasorelaxing activities of gamma-butyrobetaine esters: Possible link to the antiischemic activities of mildronate. European Journal of Pharmacology, 495(1), 67-73. doi:10.1016/j.ejphar.2004.05.006; https://pubmed.ncbi.nlm.nih.gov/15219822