We often say that we have to care for the skin, but how long have we actually practiced it once? Over the years, international health company Lycored has come to realize that maintaining skin health is a lifelong journey.
In 2016, Lekan Reid's research revealed the potential of tomato phytonutrients in skin care, which helps to understand the molecular mechanisms of tomato plant nutrients supporting skin health from the inside out. Inspired by this research, the company is actively exploring ways to provide consumers with unique, take-able solutions that enhance all-weather body care to enhance natural synergies and maximize skin benefits. In this way, the quality second-generation skin care product LycodermM was born. Lycoderm consists of tomato phytonutrients and rosemary leaf extract, a proprietary synergistic blend.
Lycored conducted research at a prestigious research center in the European Union. This large-scale, double-blind, placebo-controlled study (145 subjects) highlighted LycodermM's ability to enhance skin's natural elasticity and balance and its UV-induced (aging of the skin). The safety, bioavailability and efficacy of the response to the number one preventable cause). This study solved physiological parameters (erythema, redness) as well as gaining insight into cell level data. Research shows that the company's patented supplement, Lycoderm, "supports skin health from the inside by improving the relationship with sun light and relieving skin inflammation. The study is currently published in the journal Skin Pharmacology and Physiology.
Ultraviolet light is considered to be the main preventable cause of skin aging, with up to 80% of facial skin aging attributed to UV exposure. Therefore, supplementing traditional local and lifestyle skin care and daily pharyngeal care by finding and controlling specific cellular processes and biomarkers provides the basis for skin cosmetic and long-term skin health.
A double-blind, placebo-controlled, parallel-group study was completed in 145 healthy men and women. Subjects were supplemented with Lycoderm IM or a placebo of the same appearance within 12 weeks. At the beginning and end of the treatment period, the skin was irradiated and biopsies were taken from untreated and UV-irradiated skin 24 hours later for subsequent RT-PCR analysis of gene expression, focusing on a panel of pro-inflammatory cytokines. In addition, blood samples were taken before, during, and at the end of the supplement to assess plasma carotenoid levels of lycopene, phytoene, and phytoene.
The study was safe and well tolerated. The erythema formation was significantly reduced in the supplement group compared to the placebo group. In addition, analysis of cytokine mRNAs in skin biopsies showed statistically significant differences in mRNA levels of IL-6 and INF between treatment groups.
The results of this study provide concrete evidence for the bioavailability of the entire carotenoid component, not only providing proper nutrition to the body and skin, but also balancing the skin's response to UV light. Interestingly, after 12 weeks of supplementation, the skin appears to be more calm at both molecular and physiological levels; at the molecular level, we see a decrease in pro-inflammatory cytokines. This more balanced state of inflammation is also reflected in the reduction in redness of the skin as measured by appropriate instrumentation.