Natural high purity active ingredient osthole 98%, because of its high purity and white color, is suitable for cosmetics. It is mainly used in acne removing and anti-inflammatory cosmetics. It can be added to various kinds of skin care products such as essence, facial mask, make-up water, cream, lotion, skin care gel and so on. The added dose in cosmetics is generally 0.5%-1.0%. In addition, osthole in cosmetics, paeoniflorin, Sophora flavescens extract and other effective ingredients are generally mixed into cosmetics, which has synergistic effect.