Olive tree leaves have been used in the Mediterranean area as traditional medicine in virtue of their healthy effects. Olive leaf extracts (OLEs) contain higher amounts of polyphenols than those detected in the extra virgin olive oil and fruit. Several lines of evidence support the cardioprotective, anti-oxidant and anti-inflammatory activities exerted by OLEs.

Studies have shown that olive lead extract could help support the immune system thanks to its anti-inflammatory fatty acids playing a role in the activation of different pathways of immune competent cells.